How does protein-energy malnutrition affect wound healing?

How does protein-energy malnutrition affect wound healing?

• A. Improves collagen synthesis
• B. Impair s collagen synthesis and immune response
• C. No effect
• D. Accelerates healing

Answer: (B)

Protein-energy malnutrition disrupts wound healing because repair depends on adequate protein and energy to build new tissue and fight infection. Collagen synthesis, a key part of the proliferative phase, requires amino acids and energy; without enough protein, fibroblasts can’t produce collagen efficiently, cross-linking is reduced, and the wound’s tensile strength and closure are delayed. At the same time, immune defenses are weakened—immune cells function poorly, phagocytosis and antibody responses decline—raising infection risk and further compromising healing. So healing is slowed and wound integrity is compromised, which is why impairment of collagen synthesis and immune response is the best description.

Protein-energy malnutrition disrupts wound healing because repair depends on adequate protein and energy to build new tissue and fight infection. Collagen synthesis, a key part of the proliferative phase, requires amino acids and energy; without enough protein, fibroblasts can’t produce collagen efficiently, cross-linking is reduced, and the wound’s tensile strength and closure are delayed. At the same time, immune defenses are weakened—immune cells function poorly, phagocytosis and antibody responses decline—raising infection risk and further compromising healing. So healing is slowed and wound integrity is compromised, which is why impairment of collagen synthesis and immune response is the best description.